The Prairie View A&M Panthers basketball team is the men's basketball team that represents Prairie View A&M University in Prairie View, Texas, United States. The school's team currently competes in the Southwestern Athletic Conference (SWAC). PVAMU won the 1962 NAIA Tournament. The Prairie View A&M-Texas Southern basketball rivalry is the most anticipated and highest attended basketball series in the SWAC. The February 2018 match up at Prairie View A&M saw a home crowd of approximately 4,000 which was the largest for the season.
The Panthers have appeared twice in the NCAA Tournament. Their record is 0–2.
The William Nicks Building is a 6,500-seat multi-purpose arena in Prairie View, Texas. It is home to the Prairie View A&M University Panthers basketball team, volleyball team, and commencement. As part of renovation projects in 2011–2012, every seat is chairback. Locker rooms were renovated in 2014. The building is nicknamed the "Baby Dome" as a result of its structural configuration.