The Mississippi Valley State Delta Devils basketball team represents Mississippi Valley State University in Itta Bena, Mississippi, in NCAA Division I competition. The school's team competes in the Southwestern Athletic Conference and plays home games in the Harrison HPER Complex. The Delta Devils are currently coached by Lindsey Hunter.
The Delta Devils have appeared in five NCAA Tournaments. Their combined record is 0–5.
R.W. Harrison HPER Complex is a 5,000-seat multi-purpose arena in Itta Bena, Mississippi. Constructed in 1977, it is home to the Mississippi Valley State University Delta Devils basketball and volleyball teams.
In 2016, $17.5 million worth of upgrades were completed to further modernize the facility and add technology classrooms.